single gene defects การใช้

But even the single gene defects more common in sperm can have large consequences.
All in all, her publications have focused on syndrome delineation, pregnancy loss, neonatal stroke, microarray abnormalities, and latterly, brain abnormalities and syndromes caused by novel single gene defects.
Other mutations that could cause arthrogryposis are : single gene defects ( X-linked recessive, autosomal recessive and autosomal dominant ), mitochondrial defects and chromosomal disorders ( for example : trisomy 18 ).
All three groups of cells would be induced to grow into neurons and the scientists will track and compare the development of the healthy neurons, the neurons with a single gene defect and those with the unidentified genetic problem.
As such, these conditions do not exhibit the single gene defect basis that is so attractive for the development of highly-specific drugs largely free of major undesirable side-effects ( " the magic bullet " ).